Findings of Cochlear Hydrops Analysis Masking Procedure (CHAMP) in Subjects with Suspected and Confirmed Meniere's Disease

Abstract

The present study was carried out to develop norms for Cochlear Hydrops Analysis Masking Procedure (CHAMP) in normal hearing subjects and to compare CHAMP results in subjects with suspected Meniere’s disease with that found in normal hearing subjects in order to validate Don et al. 's (2005) study. Two groups, of participants were considered. The subjects in the control group included 30 normal hearing ears. The experimental group included 30 ears with Meniere's disease. These subjects were further classified into two groups, i.e., those with definite Meniere's disease and those with possible/probable Meniere's disease basing on the AAO-HNS guidelines . CHAMP recording was done for click alone and, click with ipsilateral pink high pass masking noise at frequencies 8,4,2,1, and 0.5 kHz. Both stimulus intensity and intensity of noise were at 60dbnHL. The results of the present study revealed that the absolute latency of wave V (ms) increasedfrom 8 kHz to 0.5 kHz HPM condition and this increase was morefor normals, lessfor definite Meniere's disease and least for possible/probable Meniere 's disease. Definite and possible /probable Meniere 's differed significantly from each other for latency shift for high frequencies (8, 4, & 2 kHz) but not for low frequencies (1 kHz & 0.5 kHz). Duration of the disease did not have any correlation with that of latency shift of wave V. The present s yields an overall specificity of CHAMP to be 76.6% and sensitivity o/ 73.3%.